Abstract: Background: Although cardiovascular disease (CVD) has been the major contributor to global mortality and disability especially in undeveloped and developing countries/areas with severer air pollutions, studies are quite limited and evidence is insufficient of short-term main air pollutants exposure on health burden of CVD hospital admissions in those regions particularly through direct costs. Method: Based on an analysis of 30,959 CVD hospital admissions among suburban farmers from 2018 to 2019 through multiple linear regression (MLR), our study evaluated the impact of main air pollutants (PM2.5, PM10, SO2, CO, NO2 and O3) exposure on number of cases, length of stay (LOS) and costs of CVD hospital admissions in Pingliang, China. Results: Concentration of SO2 and O3 rising from a low level was found to lower the costs, LOS and daily cases of CVD hospital admissions and PM2.5, PM10, CO and NO2 were found to aggravate the burden. Besides, the NO2 could put more economic stress on those CVD patients in Pingliang (China) which implies that some improvements could be done on public medical insurance policy and benefit local suburban farmers by strengthening the supports on specific drugs and therapies. Conclusions: More efforts should be made to lower the concentration of air pollution by coordinated control managements even in a low-level scenario. Concentration levels and interactions between main air pollutants may play an important role in air pollution-induced CVD health burden. Future research is needed to explore more evidence in different areas, especially with low-level SO2 effects.

Keywords: Cardiovascular disease; Hospital admission · Health burden · Main air pollutants · Public medical insurance expenditure · Northwest China · Multiple linear regression

基金资助：This work was supported by the Belt and Road Special Project of Lanzhou University (No.2018ldbryb026), the Key Project of  China Ministry of Education for Philosophy and Social Science (No.16JZD023) and the Fundamental Research Funds for the Central Universities (No.020jbkyzy037).

原文链接：https://link.springer.com/article/10.1007/s11356-022-18870-3